Quando comincia a fare effetto il Brintellix?
Sommario
Quando comincia a fare effetto il Brintellix?
La vortioxetina (principio attivo del Brintellix) mediamente inizia a funzionare dopo circa due settimane.
Cosa contiene il Brintellix?
Brintellix contiene il principio attivo vortioxetina. Appartiene al gruppo dei medicinali chiamati antidepressivi. Brintellix è usato per il trattamento degli episodi depressivi maggiori negli adulti.
What is Vortioxetine used to treat?
- Vortioxetine is an antidepressant that is used to treat major depressive disorder in adults. Vortioxetine may also be used for purposes not listed in this medication guide. Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms.
Is Vortioxetine effective in the treatment of generalized anxiety disorder (GAD)?
- Interestingly, the efficacy of vortioxetine therapy in reducing anxiety symptom severity in GAD is summarised in two previous meta-analyses. 18 19 Both reviews analysed its efficacy only in terms of symptom severity on the underlying continuous rating scales, and did not assess dichotomous outcomes of response and remission rates.
What is the Ki level of vortioxetine?
- Vortioxetine also displays binding affinities to other serotonin (5-HT) receptors, including 5-HT3, 5-HT1A, and 5-HT7, with Ki values of 3.7 nM, 15 nM, and 19 nM, respectively. There is moderate affinity toward serotonin receptors 5-HT1Dand 5-HT1B, with Ki values of 54 nM and 33 nM, respectively.
How long does it take for vortioxetine to reach peak concentration?
- Vortioxetine reaches peak plasma concentration (C max) within 7 to 11 hours post-administration (T max ), and its mean terminal half-life (T ½) is ≈ 66 hours. Steady-state mean Cmax values were 9, 18, and 33 ng/mL following doses of 5, 10, and 20 mg/day.
