Quali valori del sangue indicano la mononucleosi?
Quali valori del sangue indicano la mononucleosi?
Interpretazione
| VCA-IgM | VCA-IgG | Possibile interpretazione |
|---|---|---|
| Negativo o positivo | Positivo | Infezione attiva (però gli anticorpi EA-D IgG possono essere rilevabili per tutta la vita nel 20% dei pazienti) |
| Negativo | Positivo | Infezione passata |
| Negativo | Positivo | Probabile riattivazione del virus |
What is the concentration of anti-EBNA-1 antibodies (IgG)?
- The Anti-EBNA-1 ELISA (IgG) is linear in the investigated concentration range (7 RU/ml to 176 RU/ml). Levels of Anti-EBNA-1 antibodies (IgG) were analysed in a group of 500 healthy blood donors using the EUROIMMUN ELISA.
How many healthy blood donors are anti-EBNA-1 positive?
- Levels of Anti-EBNA-1 antibodies (IgG) were analysed in a group of 500 healthy blood donors using the EUROIMMUN ELISA. With a cut-off of 20 RU/ml, 93 % of the blood donors were anti-EBNA-1 positive (IgG), in agreement with the known infection level in adults.
How long does it take for EBNA antibodies to show up?
- Antibody to EBNA, determined by the standard immunofluorescent test, is not seen in the acute phase of EBV infection but slowly appears two to four months after onset of symptoms and persists for the rest of a person’s life. Other EBNA enzyme immunoassays may report false positive results.
How long does it take for EBV IgG levels to drop?
- Anti-VCA IgG appears in the acute phase of EBV infection, peaks at two to four weeks after onset, declines slightly then persists for the rest of a person’s life. Early antigen (EA) Anti-EA IgG appears in the acute phase of illness and generally falls to undetectable levels after three to six months.
