What is the life expectancy of someone with Waldenstrom's macroglobulinemia?
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- What is the life expectancy of someone with Waldenstrom's macroglobulinemia?
- Is Waldenstrom's curable?
- How do you get Waldenstrom?
- What is the difference between multiple myeloma and Waldenstrom's macroglobulinemia?
- What is Waldenstrom's Macroglobulinemia symptoms?
- What are the end stages of Waldenstrom's?
- Is Waldenstrom's painful?
- Is Waldenstrom's macroglobulinemia a lymphoma?
- How rare is Waldenstrom's Macroglobulinemia?
- What are the symptoms of macroglobulinemia?
- What is winwaldenstrom macroglobulinemia?
- What are the complications of Waldenstrom macroglobulinemia?
- What are the treatment options for immunoglobulin M (IgM) deficiency?
What is the life expectancy of someone with Waldenstrom's macroglobulinemia?
According to the National Cancer Institute's SEER database (based on people diagnosed between 20), the overall relative 5-year survival of people with WM is about 78%....Median survival.
| ISSWM risk group | Median survival* |
|---|---|
| Low | 12 years |
| Intermediate | 8 years |
| High | 3.5 years |
Is Waldenstrom's curable?
Waldenstrom macroglobulinemia (WM) is generally not considered to be curable, but it is treatable. Many different medicines can help keep WM under control, often for long periods of time. Not everyone with WM needs treatment right away. In fact, some people are diagnosed with WM before they even have symptoms from it.
How do you get Waldenstrom?
The DNA changes found in WM cells are usually acquired after birth (not passed on from a parent). Some of these acquired changes may have outside causes, but often they occur for no apparent reason. They seem to happen more often as we age, which might help explain why WM usually occurs in older people.
What is the difference between multiple myeloma and Waldenstrom's macroglobulinemia?
Multiple myeloma is a cancer of plasma cells; non-Hodgkin lymphoma is a cancer of lymphocytes. Waldenstrom's cells have features of both plasma cells and lymphocytes; Waldenstrom's is a lymphoplasmacytic lymphoma.
What is Waldenstrom's Macroglobulinemia symptoms?
Symptoms
- Easy bruising.
- Bleeding from the nose or the gums.
- Fatigue.
- Weight loss.
- Numbness in your hands or feet.
- Fever.
- Headache.
- Shortness of breath.
What are the end stages of Waldenstrom's?
Staging/Prognostic Scoring System for Waldenstrom Macroglobulinemia/Lymphoplasmacytic Lymphoma
| Score | Stage | 5-year overall survival |
|---|---|---|
| 1 | Low | 86% |
| 2 | Intermediate | 78% |
| 3 | High | 47% |
| 4-5 | Very high | 36% |
Is Waldenstrom's painful?
Neuropathy: In some people with WM, the abnormal antibody can attack and damage nerves outside the brain. This can lead to numbness or a painful “pins and needles” sensation in the feet and legs, which is called neuropathy.
Is Waldenstrom's macroglobulinemia a lymphoma?
Waldenstrom macroglobulinemia (WM) is a type of non-Hodgkin lymphoma (NHL). The cancer cells make large amounts of an abnormal protein (called a macroglobulin). Another name for WM is lymphoplasmacytic lymphoma.
How rare is Waldenstrom's Macroglobulinemia?
Waldenstrom macroglobulinemia (WM) is rare, with an incidence rate of about 3 cases per million people per year in the United States. About 1,000 to 1,500 people are diagnosed with WM each year in the United States.
What are the symptoms of macroglobulinemia?
- Macroglobulinemia is a plasma cell cancer in which a single clone of plasma cells produces excessive amounts of a certain type of large antibody (IgM) called macroglobulins. Although many people have no symptoms, some people have abnormal bleeding, recurring bacterial infections, and bone fractures due to severe osteoporosis.
What is winwaldenstrom macroglobulinemia?
- Waldenstrom macroglobulinemia (WM) is a type of non-Hodgkin lymphoma (NHL) . The cancer cells make large amounts of an abnormal protein (called a macroglobulin).
What are the complications of Waldenstrom macroglobulinemia?
- If you have Waldenstrom macroglobulinemia, your bone marrow produces too many abnormal white blood cells that crowd out healthy blood cells. The abnormal white blood cells produce a protein that accumulates in the blood, impairs circulation and causes complications. Waldenstrom macroglobulinemia is considered a type of non-Hodgkin's lymphoma.
What are the treatment options for immunoglobulin M (IgM) deficiency?
- This involves removing the blood, passing it through a machine that removes the part of the blood with the IgM antibody, and returning the blood to the body. This may be combined with other treatments such as various types of chemotherapy.
