What is Jod Basedow phenomenon?

What is Jod Basedow phenomenon?

Jod-Basedow phenomenon occurs due to either overactivation of the entire thyroid gland or, more commonly, autonomous nodules within the gland after iodine repletion without adequate feedback control from the pituitary gland. This escape from the protective Wolff-Chaikoff effect is called the Jod-Basedow phenomenon.

How is Basedow treated?

How is Graves Basedow treated? Once diagnosed, treatment with oral antithyroids (carbimazole, methimazole, propylthiouracil), which inhibit the formation of thyroid hormones and will achieve an improvement in symptoms within 7-15 days, should be instituted.

Is Basedow disease curable?

Symptoms of Basedow's disease can be wide-ranging, including anxiety, diarrhea, and skin abnormalities. However, there are safe and effective treatment options that help most people with this condition live long, full lives.

Why is it called Basedow's disease?

Age distribution of patients with Basedow's disease at the time of their first visit to Ito Hospital(4,129 new patients in 2015) Basedow's disease was named after the German physician, Carl von Basedow, who published research on this disease in 1840.

What does methimazole do to the body?

Methimazole prevents the thyroid gland from producing too much thyroid hormone. Methimazole is used to treat hyperthyroidism (overactive thyroid). It is also used before thyroid surgery or radioactive iodine treatment.

What causes de Quervain's thyroiditis?

De Quervain's (subacute) thyroiditis is a painful swelling of the thyroid gland thought to be triggered by a viral infection, such as mumps or flu. It's most commonly seen in women aged 20 to 50. It usually causes high temperature and pain in the neck, jaw or ear.

How is thyroid eye disease diagnosed?

HOW IS THE DIAGNOSIS MADE? If you have already been diagnosed with hyperthyroidism, a doctor may diagnose Graves' eye disease by examining your eyes and finding swelling and enlargement of the eye muscles. A computed tomography (CT) scan or magnetic resonance imaging (MRI) scan of the eye muscles may be helpful.

Does Graves disease shorten your life?

Patients who develop thyroid storm have a 20 to 50% chance of dying. In general, if your hyperthyroidism is caught early and you control it well with medication or other options, experts say your Graves' disease life expectancy and prognosis is favorable.

Will my eyes go back to normal after Graves disease?

In most patients who develop Graves' ophthalmopathy, the eyes bulge forward or the eyelid retracts to some degree. Many patients with mild to moderate Graves' ophthalmopathy will experience spontaneous improvement over the course of two to three years or will adapt to the abnormality.

Will I gain weight after treating hyperthyroidism?

Treatment of hyperthyroidism commonly results in weight gain, but the extent of weight gain is not well known. Patients may regain the weight they had lost or may overshoot and become obese.

What were Basedow's views on philosophy based on?

• Basedow’s views were based on the writings of men such as John Amos Comenius, John Locke, and Jean-Jacques Rousseau.

What is Jod-Basedow disease?

• Basedow disease - Synonym (s): Graves disease; thyrotoxicosis Basedow goiter - colloid goiter which becomes hyperfunctional after the ingestion of excess iodine, causing Jod-Basedow phenomenon. Basedow pseudoparaplegia - weakness of the thigh muscles in thyrotoxicosis. Basedow syndrome - myeloneuropathy seen in the presence of thyrotoxicosis.

What did John Basedow do to his students?

• The performances of his first pupils profoundly impressed observers, including Immanuel Kant and Johann Wolfgang von Goethe. However, his heavy drinking and emotional outbursts drove away the better teachers, and in 1784 Basedow severed his connection with the school.

What is the difference between Graves disease and Basedow's disease?

• The clinical triad described by Basedow included goiter, exophthalmos, and tachyardia. On the European Continent the term Basedow's disease is the more common, while it is known as Graves' disease in the English-speaking world.