What does high EBV VCA IgG mean?

What does high EBV VCA IgG mean?

In general, rising VCA-IgG levels tend to indicate an active EBV infection, while falling concentrations tend to indicate a recent EBV infection that is resolving.

What is IgG anti VCA?

Anti-EBV (VCA) IgG is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against Epstein-Barr virus viral capsid antigen (VCA) in human serum or plasma.

What is a normal EBV VCA IgG level?

Optimal Result: 0 - 17.9 U/mL.

How long does EBV IgG stay positive?

Viral capsid antigen (VCA) Anti-VCA IgM appears early in EBV infection and usually disappears within four to six weeks. Anti-VCA IgG appears in the acute phase of EBV infection, peaks at two to four weeks after onset, declines slightly then persists for the rest of a person's life.

What does EBV VCA IgM mean?

The presence of VCA IgG antibodies indicates that an EBV infection has occurred at some time recently or in the past. The presence of VCA IgM antibodies and the absence of antibodies to EBNA mean that the infection has occurred recently. The presence of antibodies to EBNA means that the infection occurred in the past.

How do I know if my EBV is reactivated?

What Are the Symptoms of EBV Reactivation?

1. Swollen tonsils.
2. Extreme fatigue.
3. Rash.
4. Sore throat.
5. Headache.
6. Enlarged spleen (splenomegaly)
7. Swollen liver.
8. Swollen lymph nodes.

Is Epstein-Barr an autoimmune disease?

Epstein-Barr infects B cells—a type of white blood cell in the immune system. This may explain the association between Epstein-Barr and the EBNA2 disorders: All seven are autoimmune diseases, conditions involving an abnormal immune response to a normal body part.

When does EBV IgG turn positive?

Although not always present, EA (D) IgG increases during the first 3-4 wk and is no longer detectable after 3-4 mo (approximately 85% of the patients with acute infection are positive for up to 3 mo after symptom onset)[23,24], even though in some cases they can still be detected years after a primary infection[23].

What does a positive EBV VCA IgG mean?

• The presence of VCA IgG antibodies indicates that an EBV infection has occurred at some time recently or in the past. The presence of VCA IgM antibodies and the absence of antibodies to EBNA mean that the infection has occurred recently. The presence of antibodies to EBNA means that the infection occurred in the past.

What is EBV AB VCA, IgM?

• EBV Ab VCA IgM Blood Test. The EBV (Epstein Barr Virus) Antibodies to Viral Capsid Antigen (VCA) IgM test looks for a type of antibody which the body develops in response to infection with Epstein-Barr Virus. IgM antibodies typically appear shortly after infection and disappears at around 4-6 weeks.

What does elevated IgG mean?

• Elevations of IgG may be due to polyclonal immunoglobulin production. Monoclonal elevations of IgG characterize multiple myeloma. Monoclonal gammopathies of all types may lead to a spike in the gamma globulin zone seen on serum protein electrophoresis.

What does a positive EBV IgG mean?

• A positive herpes IgG test, if the test result is accurate, means that your body has been infected with the herpes simplex virus. Furthermore, type specific HSV IgG tests can be used to distinguish between HSV-1 and HSV-2.